1. Meng Yu - Knowlton School - The Ohio State University
Bevat niet: Zeng | Resultaten tonen met:Zeng
Meng Yu is a fifth-year Ph.D. candidate in City and Regional Planning (Fall 2020-present). Advised by Prof. Jennifer Clark, her research interests cover regional planning with a special focus on "sustainable agglomeration" oriented transportation infrastructure planning, financial arrangements, intermediate industries and institutional remaking for partnership at a regional scale in developing countries.
2. 618. Acute Myeloid Leukemias: Biomarkers and Molecular Markers ...
13The Ohio State University Comprehensive Cancer Center, The Ohio state University, Columbus, OH ... Zeng, BSc1,2 and John E. Dick, PhD1,2. 1Princess ...
Symposia: Acute Myeloid Leukemias: Biomarkers and Molecular Markers in Diagnosis and Prognosis Program: Oral and Poster Abstracts Type: Poster Hematology Disease Topics & Pathways:Research, Acquired Marrow Failure Syndromes, Acute Myeloid Malignancies, Combination therapy, AML, MDS, Fundamental Science, Clinical trials, Adult, Clinical Practice (Health Services and Quality), Bone Marrow Failure Syndromes, Drug development, APL, MPN, Translational Research, Assays, Elderly, Genomics, Bioinformatics, Chemotherapy, Clinical Research, Health outcomes research, Hematopoiesis, Chronic Myeloid Malignancies, CMML, Pediatric, Diseases, Immune mechanism, Treatment Considerations, Biological therapies, Immunology, Immunotherapy, Real-world evidence, Adverse Events, Non-Biological therapies, Metabolism, Computational biology, Young adult , Biological Processes, Myeloid Malignancies, Technology and Procedures, Molecular biology, Study Population, Multi-systemic interactions, Profiling, Human, Pathogenesis, Measurable Residual Disease , Animal model, Machine learning, Molecular testing, Omics technologies
3. [PDF] 6th Annual EEIC Engineering Capstone Design Showcase
29 mei 2024 · The Showcase is a platform for individual, multidisciplinary and industry-spon¬sored student projects which enables Ohio State engineer¬ing ...
4. Adaptive design of mRNA-loaded extracellular vesicles for targeted ...
19 okt 2023 · We show an adaptive strategy that enables the docking of different targeting ligands onto the surface of mRNA-loaded small extracellular vesicles (sEVs).
The recent success of mRNA therapeutics against pathogenic infections has increased interest in their use for other human diseases including cancer. However, the precise delivery of the genetic cargo to cells and tissues of interest remains challenging. Here, we show an adaptive strategy that enables the docking of different targeting ligands onto the surface of mRNA-loaded small extracellular vesicles (sEVs). This is achieved by using a microfluidic electroporation approach in which a combination of nano- and milli-second pulses produces large amounts of IFN-γ mRNA-loaded sEVs with CD64 overexpressed on their surface. The CD64 molecule serves as an adaptor to dock targeting ligands, such as anti-CD71 and anti-programmed cell death-ligand 1 (PD-L1) antibodies. The resulting immunogenic sEVs (imsEV) preferentially target glioblastoma cells and generate potent antitumour activities in vivo, including against tumours intrinsically resistant to immunotherapy. Together, these results provide an adaptive approach to engineering mRNA-loaded sEVs with targeting functionality and pave the way for their adoption in cancer immunotherapy applications. There is an emerging interest in the use of mRNA therapeutics in cancer treatment, but their precise in vivo delivery remains a challenge. Here the authors develop IFN-γ mRNA-loaded small extracellular vesicles (sEVs) with CD64 overexpressed on their surface and demonstrate its efficacy in glioblastoma mouse models resistant to immunotherap...
5. Reduced Ca2+ transient amplitudes may signify increased or decreased ...
22 jul 2022 · Reduced Ca2+ transient amplitudes may signify increased or decreased depolarization depending on the neuromodulatory signaling pathway · Abstract.
Neuromodulators regulate neuronal excitability and bias neural circuit outputs. Optical recording of neuronal Ca2+ transients is a powerful approach to study the impact of neuromodulators on neural circuit dynamics. We are investigating the ...
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6. Past Recipients - Materials Research Society
View our Graduate Student Award Finalists (PDF) Gold Winners Silver Winners Arthur Nowick Graduate Student Award Recipient
View our Graduate Student Award Finalists (PDF)
7. 2024 China Financial Research Conference - Editorial Express
6 jul 2024 · 26 sessions, 72 papers, and 0 presentations with no associated papers. 2024 China Financial Research Conference. Detailed List of Sessions.
8. Research Track Papers - ACM KDD 2024
Research Track Papers Schedule Tuesday, August 27 11:00-13:00, Room 116 Theme: LLMs Session Chair: Carl Yang (Emory University)
Research Track Papers Schedule Tuesday, August 27 11:00-13:00, Room 116Theme: LLMsSession Chair: Carl Yang (Emory University) On Early Detection of Hallucinations in Factual Question Answering Ben Snyder (Amazon Web Services); Marius Moisescu (Amazon Web Services); Muhammad Bilal Zafar (Ruhr-Universität Bochum, Research Center for Trustworthy Data Science and Security, University Alliance Ruhr) A Hierarchical Context Augmentation […]
9. Heming Wang
About Me · PhD in Computer Science and Engineering, in progress. The Ohio State University · MMath in Applied Mathematics, 2018. University of Waterloo · BSc in ...
Research Scientist
